High Purity Orlistat Powder Raw Material

Shandong Guanqing Food Ingredient Co., Ltd. is the only company in China that has been approved for chemical weight-loss raw material drugs and is globally recognized as a non-prescription weight-loss raw powder. It works by inhibiting fat absorption, achieving significant weight loss results with high safety.
Our company has launched the raw powder of orlistat (CAS: 96829-58-2) as a high-purity medicinal raw material, with a purity of ≥ 99.5% and impurity content meeting the standards of domestic and international pharmacopoeias. It takes effect locally in the intestines, does not enter the bloodstream, has no systemic side effects, and is safe and mild. It can block the absorption of dietary fat, reduce fat while assisting in regulating blood lipids and improving metabolism. The production process is mature, batch stability is good, and storage performance is excellent. It is a globally recognized compliant weight-loss raw material, suitable for various production needs such as preparations, health supplements, etc.

Mechanism of Action
Selectively inhibits gastrointestinal lipase, blocking fat breakdown. The undigested fat cannot be absorbed by the intestines and is directly excreted in the feces, reducing calorie intake at the source. It only takes effect locally in the intestines and hardly enters the bloodstream.
Main Effects
1. Weight control: Reduce the absorption of dietary fat, lower body fat, lose weight, and maintain the weight loss effect.
2. Regulate blood lipids: Reduce triglycerides and cholesterol in the blood, and improve the problem of high blood lipids.
3. Improve metabolism: Helps enhance insulin sensitivity and has a regulatory effect on metabolic abnormalities associated with obesity.
Applicable Scenarios
It is mainly used for weight management in obese and overweight individuals, and can also assist in the intervention of lipid abnormalities and metabolic syndrome caused by obesity.
The results are as follows

Core Advantages (Applications and Market)

 

 

High compliance

The only OTC weight loss drug approved by FDA/EMA/NMPA. The raw materials have high global recognition, and the application and certification thresholds are low.

Weight loss + improvement of chronic diseases

In addition to fat and weight loss, it can also lower blood lipids, improve insulin resistance, assist in controlling blood sugar and blood pressure, and is suitable for obese individuals with metabolic problems.

Fast onset, good compliance

Obvious oil excretion effect can be observed 24-48 hours after taking the medication; taken during meals, no need for diet restriction or diarrhea, suitable for long-term management.

Raw material source is mature

Biological fermentation and semi-synthetic processes are carried out concurrently, with green and environmentally friendly characteristics and stable production capacity; Leading domestic enterprises have already overcome the high-purity purification technology, and the cost is controllable.

Side effects are mild and controllable

Mainly transient gastrointestinal reactions (such as oily stools and frequent flatulence), which can be significantly reduced with a low-fat diet; there is no risk of liver or kidney toxicity (rare cases of liver damage are attributed to specific individual reactions).

Name	Orlistat raw material powder
CAS Number	96829-58-2
Molecular formula	C29H53NO5
Molecular weight	495.73
Molecular structure diagram
Appearance	White or off-white crystalline powder
Solubility	It is almost insoluble in water, but readily soluble in trichloromethane, and slightly soluble in ethanol and methanol.
Melting point	42～47 ℃
Specific rotation	-28.0° to -32.0° (c = 1, chloroform)
Water	≤0.5%
Scorched residues	≤0.1%
Heavy Metal	≤10 ppm
Content	≥99.5%(HPLC)
Single substance related to matter	≤0.1%
There is always matter involved	≤0.5%
Optical isomer	≤0.1%