Shandong Guanqing Food Ingredient Co., Ltd. is a professional producer of pharmaceutical raw powder in the pharmaceutical raw material powder industry. We provide high-purity sibutramine raw powder for global manufacturers, research and development, and production of weight loss raw powder and health care raw powder. We adopt advanced synthesis and extraction technology, with a high content of 99% sibutramine (CAS 106650-56-0), which is specifically for female weight loss raw powder. The mechanism of action of sibutramine raw powder is: by inhibiting the reuptake of monoamine information transmission factors such as 5-HT and norepinephrine in cells, it increases the physiological feeling of fullness, reduces appetite, induces thermogenesis, increases energy consumption, and reduces fat accumulation. It is mainly used for diet control, when exercise cannot reduce and control obesity, for the treatment of obesity. It was first launched in April 1998 as a reuptake inhibitor of norepinephrine and 5-HT.
What is the Effect of Sibutramine Powder?
1. Suppress appetite: acts on the brain center, reduces hunger, eats less food, reduces calorie intake, and shows significant short-term weight loss;
2. Enhance metabolism: excites the sympathetic nerve, accelerates energy consumption, assists in weight loss.
3. Efficient fat burning: blocks carbohydrates, assists in calorie control, dietary fiber satiates, daily weight management, dietary supplementation, meal savior.
4. Assist metabolism, balance diet, block fat absorption
5. Post-meal blocking, weight control care, fruit and vegetable extracts
6. Test effect pictures are as follows.
Product Parameters
| Name | Sibutramin raw material powder |
| CAS Number |
106650-56-0 |
| Water | 5.0-6.0% |
| Storage conditions | Sealed, dry, cool place (2 - 8°C is preferred) |
| Structural formula | Physical properties: White crystalline powder |
| Molecular formula |
C17H29NOCl2 |
| Molecular weight |
334.33 |
| Melting point |
191-192℃ |
| Physical properties - Melting point | 191-192°C |
| Solubility | 2.9 mg/ml |
| Content |
99% |
| Solubility | Soluble in methanol and ethanol, slightly soluble in water |
| Molecular structure |  |
Advantages and Features
Purity testing: The international standard content is 99% with impurity levels below 1%. Each batch is tested for heavy metals (<20ppm), residual solvents and moisture content. Batch consistency: Strict manufacturing control ensures that the quality of each production run is the same, eliminating experimental variations.
Mix p-chlorobenzyl cyanate, KOH and acetonitrile, and slowly add 1,3-bromopropane dropwise at 25℃. After the reaction is complete, add distilled water and then extract with ethyl acetate. The extract is washed with water and saturated brine, dried. Filter, evaporate under reduced pressure, and then distill to obtain the compound. Dissolve magnesium sheet in THF, add isobutyl bromide, and then react. Slowly add the THF solution of the obtained compound to the reaction mixture and reflux. After treatment, the obtained compound reacts with acetic acid and formaldehyde solution, is stirred, and slowly added into the crushed ice solution of sodium hydroxide, then extracted with ethyl ether. The extract is washed with saturated brine and water, dried. Filter, and concentrate the filtrate to obtain sibutramine.
Source factory offers immediate delivery, flexible orders with low minimum quantity requirements, complete quality inspection for safe supply, can be divided and shipped in batches, compliant food raw material powder.
On-site supply,
Stable supply chain: strong inventory and monthly production capacity to meet long-term project needs.
Global flexible transportation: safe, temperature-appropriate packaging, and complete customs documents attached for smooth delivery worldwide.
COA quality inspection report, factory release report, specification manual, MSDS (Material Safety Data Sheet), product technical specification, commercial inspection materials, customs declaration documents, compliance qualifications, production qualifications, traceability documents, third-party testing report, factory inspection, original factory documents, ingredient parameters, physical and chemical indicators, packaging filing materials, complete set of documents.
Packaging and Delivery
Packaging Specifications
Small quantity: 1kg/5kg/10kg aluminum foil bags, with thick waterproof inner film bags for sealing packaging
Large quantity: 25kg standard export cardboard barrels/linen paper barrels/plastic barrels, sturdy and pressure-resistant, not prone to deformation
All double-layer sealed, completely preventing moisture absorption, clumping, leakage and contamination.
Delivery Channel
Support DHL, FedEx, UPS, EMS, sea transportation, air transportation, and multi-channel delivery;
The freight forwarding resources are stable, and we can follow the progress of the goods logistics, customs declaration, and release throughout the process, and promptly synchronize the logistics information to the customers.
Payment methods: Telegraphic Transfer, Western Union Transfer, MoneyGram, Letter of Credit
Delivery Period
Regular stock: Shipment will be made within 24-48 hours after payment confirmation.
Customized packaging/special specifications: Shipment will be arranged within 3-7 working days.
During peak seasons, large-volume orders will be pre-ordered to ensure timely delivery.
After-sales Guarantee
Pre-sales service
Technical Consultation: A professional team provides product parameters, application plans and compliance guidance, and answers questions related to research and production.
Sample Assurance: Before placing an order, a sample for testing can be provided (shipping cost is at your own expense). If the sample indicators do not match the main product, the order can be cancelled without any conditions.
Pre-sale service
Order Tracking: Real-time synchronization of production progress, delivery status and logistics information. Customers can query at any time.
Quality Communication: Each batch of products undergoes re-inspection and confirmation before shipment, and test results are promptly provided to ensure product quality.
Customized Cooperation: Adjust purity, packaging and documents according to customer needs to meet the requirements of personalized orders.
After-sales service
Quality Assurance: If there are any quality issues with the product within 7 days after delivery, it can be returned and exchanged for free. The shipping cost will be borne by us.
Technical Support: Provide subsequent technical guidance, such as formula optimization, process adjustment, and compliance declaration.
Long-term Cooperation: Establish customer files, offer priority supply, preferential prices, and exclusive services to ensure long-term stable cooperation.
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