Semaglutide sodium salt API powder (CAS No. 910463-68-2) is produced via advanced peptide synthesis and rigorous purification processes. Characterized by high purity and low impurity levels, the powder is free from clumping or discoloration and exhibits excellent solubility in buffer systems, making it a core peptide raw material for GLP-1 target mechanism research and the development of new anti-diabetic and weight-loss drugs. Continuous stock is maintained, and packaging specifications are flexibly customizable.
Produced using a solid-phase peptide synthesis system combined with multi-stage chromatography purification, this Semaglutide sodium salt API differs from the free-peptide form; the sodium salt configuration optimizes dissolution efficiency and stability during room-temperature storage, resulting in a fluffy, homogeneous, fine white crystalline powder. Backed by a comprehensive, closed-loop quality control system, the product consistently achieves an HPLC-verified purity of 99% or higher, with individual and total impurity levels strictly controlled within industry-leading ranges. A Certificate of Analysis (COA), HPLC chromatograms, and mass spectrometry identification reports are provided for every batch.
Product Overview
This product is a high-purity peptide active pharmaceutical ingredient (API)-specifically, semaglutide sodium salt-produced through solid-phase synthesis, multi-stage purification, and low-temperature lyophilization. Compared to standard free-form peptides, the sodium salt modification significantly enhances powder stability, water solubility, and formulation compatibility. The final product is a uniform, white, loose crystalline powder characterized by high color purity, the absence of caking or off-odors, and a lack of discolored particles.
Manufactured under rigorous, precision quality control, the product boasts an HPLC purity of ≥99%, with strict limits on individual and total impurities. It exhibits minimal batch-to-batch variation and a stable structure resistant to degradation. As a core raw material for next-generation long-acting GLP-1 receptor agonists, it is widely utilized in fields such as drug mechanism research, pharmacological studies, formulation development, and pharmaceutical scientific research.
Key Product Features

High Purity with Minimal Impurities
Utilizing a repeated chromatographic purification process, the product effectively removes synthesis residues, truncated peptides, and isomeric impurities. It consistently meets purity standards and ensures high data reproducibility, without interfering with experimental or formulation outcomes.
Enhanced Structural Stability (Sodium Salt Form)
The sodium salt form optimizes the molecule's hydrophilic structure. Compared to standard Semaglutide free peptides, it exhibits lower hygroscopicity, superior storage stability, and faster dissolution, making it compatible with a wide range of buffer solutions and solvent systems.
Excellent Powder Quality
Produced via lyophilization, the powder is fine and fluffy with uniform coloration. It dissolves into a clear, transparent solution free of insoluble residue, making it ideal for high-end R&D and pharmaceutical formulation development.
Batch-to-Batch Consistency and Long-Term Supply
Manufactured on standardized synthesis lines, every batch undergoes comprehensive testing-including HPLC, mass spectrometry (MS), moisture content, and visual inspection. With traceable data and consistent quality, the product is suitable for long-term partnerships with research institutions and pharmaceutical companies.
Safety, Compliance, and Comprehensive Documentation
We provide COA reports, HPLC chromatograms, MS reports, and factory test data. Third-party re-testing is supported, ensuring compliance with standards for export, laboratory audits, and pharmaceutical R&D reviews.
Basic Product Specifications
| Name | Semaglutide Sodium |
| CAS No. | 910463-68-2 |
| Appearance | White to off-white crystalline powder |
| Purity | ≥99% (HPLC) |
| Storage Conditions | Store at -20°C in a sealed, dry place, protected from light |
| Shipping Method | Cold-chain transport |
| Packaging Specifications | 1g/50g/25kg (fiber drum) or vacuum-packed in aluminum foil |

Main Areas of Application

Medical and Scientific Research
Suitable for universities, laboratories, and research institutes conducting basic pharmacological studies-such as blood glucose regulation, lipid metabolism, body weight control, and GLP-1 target mechanisms-yielding stable and highly reproducible experimental data.
New Drug Formulation Development
Used by pharmaceutical companies for long-acting peptide formulations, lyophilized products, sustained-release formulas, injection formulation development, process optimization, stability testing, and preliminary R&D trials.
Experimental Models
Used in research projects involving the establishment of pharmacological models (for blood glucose reduction, fat loss, and metabolic conditions), efficacy evaluation, and tolerability testing.
In vitro activity testing
Used for R&D activities such as cellular-level activity verification, molecular mechanism analysis, comparative drug testing, and raw material stability assessment.
Our Factory's Supply Advantages
1. Direct manufacturer with in-house R&D and production; stable inventory; supports everything from small sample orders to large-scale, long-term contracts.
2. Fully stocked and direct-to-customer (no middlemen); rapid dispatch; supports global export orders.
3. Supports custom packaging/aliquoting and specific testing requirements; provides project-specific documentation tailored to client needs.
4. Strict low-temperature protocols for production, aliquoting, and storage to maximize the stability and activity of the peptides.
5. Professional export team familiar with international standards; provides complete customs clearance documentation and technical after-sales support.
After-Sales Support
Pre-sales Service
Technical Consultation: A professional team provides product specifications, application solutions, and regulatory guidance, while addressing inquiries related to R&D and production.
Sample Support: Small samples are available for testing prior to order placement (shipping costs borne by the customer); orders may be cancelled unconditionally if sample specifications do not match the bulk shipment.
In-sales Service
Order Tracking: Real-time updates on production progress, shipment status, and logistics information are available for customer inquiry at any time.
Quality Communication: Each batch undergoes re-inspection and verification before shipment, with test results promptly communicated to ensure product quality.
Customization: Purity levels, packaging, and documentation can be adjusted to meet specific customer requirements and personalized orders.
After-sales Service
Quality Guarantee: Free returns and exchanges are provided for any quality issues identified within 7 days of delivery, with shipping costs covered by us.
Technical Support: Ongoing technical guidance is offered, including formula optimization, process adjustments, and regulatory compliance statements.
Long-term Partnership: We maintain customer profiles and offer priority supply, preferential pricing, and dedicated service to ensure a stable, long-term partnership.
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