Cetilistat raw material powder (CAS: 282526-98-1)-chemically known as 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one-is a next-generation, highly selective gastrointestinal lipase inhibitor used for weight loss. As an upgraded alternative to Orlistat, it offers advantages such as fewer side effects, better tolerability, and consistent efficacy, making it widely used in the production of premium weight management formulations and fat-loss medications. The product appears as a fine crystalline powder with stable physicochemical properties and a purity exceeding 99%; it features low impurity levels and strong batch-to-batch consistency, fully complying with production standards for pharmaceutical and food-grade health supplements. Cetilistat operates via a specific mechanism, acting locally within the gastrointestinal tract without entering the bloodstream or stimulating the central nervous system; by potently inhibiting gastric and pancreatic lipase activity, it blocks the breakdown and absorption of dietary fat, thereby reducing caloric accumulation at the source and effectively aiding in fat loss and weight control. It significantly mitigates common adverse reactions associated with traditional fat-loss ingredients, such as embarrassing oily discharge and gastrointestinal discomfort. With a mature production process and stable supply, the product supports sample testing, bulk shipments, and customized packaging; it remains stable during long-term storage at room temperature (when sealed and protected from light) and is suitable for developing various finished products, including tablets, capsules, and dietary supplements. It is currently a preferred high-quality fat-loss ingredient for cross-border trade, pharmaceutical companies, and health brands.
What are the Effects of Cetilistat Raw Powder?
Blocks fat absorption and reduces caloric intake
It binds to and inhibits gastric and pancreatic lipases, preventing dietary triglycerides from breaking down into absorbable fatty acids. Undigested fat is excreted directly; it inhibits the absorption of approximately 30% of dietary fat per meal, preventing excess oil from being stored in the body.
Promotes steady weight loss and reduces body fat
Long-term use creates a caloric deficit by reducing daily absorption by several hundred kilocalories. When combined with a standard diet, most users achieve steady weight loss of 0.5–1.2 kg per week, with a primary reduction in visceral and abdominal fat.
Helps regulate blood lipid levels
By continuously reducing fat absorption, it lowers total blood cholesterol, triglycerides, and low-density lipoprotein (LDL) levels, making it suitable for individuals with obesity and hyperlipidemia.
Improves conditions for obesity with Type 2 diabetes
Weight loss combined with reduced fat absorption enhances insulin sensitivity, helping to stabilize blood glucose and HbA1c levels, and potentially reducing the required dosage of anti-diabetic medication.
What are the Advantages of Our Products and Factories?
Product Quality Advantages
1. High Purity and Consistent Grade
Purity ≥99% (HPLC compliant); strict controls on heavy metals, microorganisms, and residual solvents (meeting USP/EP/Food Grade standards). Minimal batch-to-batch variation ensures stable quality for long-term mass production, making it suitable for compliant manufacturing of pharmaceutical formulations and dietary supplements.
2. Superior Efficacy and Lower Side Effects than Orlistat
Matches fat-inhibition efficiency at equivalent dosages while significantly reducing the incidence of oily discharge, diarrhea, flatulence, and fecal incontinence. Results in higher user compliance and stronger product repurchase rates. Acts locally within the intestine without entering the bloodstream or affecting the central nervous system; free from side effects such as dizziness, palpitations, or insomnia.
3. Excellent Physicochemical Properties
Fine white powder with good flowability; easy to blend for tableting or capsule filling and resistant to caking. Compatible with various manufacturing processes-including tablets, hard capsules, and powders-facilitating convenient downstream processing.
Factory and Supply Chain Advantages
1. Direct Manufacturer; No Middlemen
Operates proprietary synthesis production lines with large-scale capacity and readily available stock. Capable of handling orders ranging from small samples (1g/10g) to tonnage-level bulk orders with short lead times and stable supply scheduling, even during peak seasons.
2. Comprehensive Qualifications and Documentation
Provides a full suite of documents, including COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), chromatograms, residual analysis reports, and sample test records. Supports third-party verification to meet requirements for overseas customs clearance, pharmaceutical company filings, and brand compliance audits.
3. Customized Services
Offers services such as ultrafine grinding, sterilization, and small-batch packaging upon request; provides technical reference support for formulations.
Basic Specifications of Cetilistat Raw Material Powder
| Basic Chemical Parameters | |
| Name | Cetilistat Raw Powder |
| CAS Number | 282526-98-1 |
| Molecular Formula | C25H39NO3 |
| Molecular Weight | 401.58 |
| Chemical Name | 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one |
| Physical Properties | |
| Appearance | White crystalline fine powder |
| Melting Point | 72–76°C |
| Water Solubility | Practically insoluble in water; soluble in ethanol and DMSO |
| Odor | Odorless |
| Purity and Quality Specifications (Industrial/Pharmaceutical Grade) | |
| Assay (HPLC) | ≥99.0% |
| Individual Impurity | ≤0.2% |
| Total Impurities | ≤1.0% |
| Moisture | ≤0.5% |
| Heavy Metals | ≤20 ppm |
Payment Information and Packaging Specifications
Payment Methods: Wire Transfer (T/T), Western Union, MoneyGram, Letter of Credit (L/C)
Delivery Lead Time
Standard stock items: Shipped within 24–48 hours of payment confirmation.
Custom packaging/Special specifications: Shipment arranged within 3–7 business days.
For large-volume orders during peak seasons, we schedule production in advance to ensure on-time delivery.
Packaging Specifications
1. Packaging customized to client requirements.
2. Our standard packaging:
Small quantities: 1kg/5kg/10kg aluminum foil bags, sealed with a thickened, waterproof inner liner.
Bulk quantities: 25kg standard export-grade cardboard drums, kraft paper drums, or plastic drums-sturdy, pressure-resistant, and deformation-resistant.
All packaging features double-layer sealing to prevent moisture, clumping, leakage, and contamination.
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